Description

Bupropion-Naltrexone (Contrave) – Dual-Action Prescription Weight Loss Pill

Looking for a clinically proven way to manage weight and reduce food cravings? Bupropion-Naltrexone, sold under the brand name Contrave, is a powerful, prescription-strength weight loss medication that combines two active ingredients to help support long-term weight management.

Contrave works by targeting key areas in the brain that influence hunger, cravings, and reward responses. Bupropion (an antidepressant) helps improve mood and reduce appetite, while naltrexone (an opioid antagonist) helps diminish food cravings and emotional eating habits.

Together, they form a highly effective weight loss solution for adults with a BMI of 30 or higher, or those with a BMI of 27+ with weight-related conditions such as high blood pressure, diabetes, or high cholesterol.

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Key Benefits:

• Supports appetite control and craving reduction

• Helps promote sustainable, long-term weight loss

• Clinically studied and FDA-approved formula

• Non-stimulant and non-habit forming

• Ideal for adults struggling with obesity or weight-related health issues

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How to Use:
Contrave is typically taken as a daily oral tablet, with the dosage gradually increased over several weeks. It should be used alongside a reduced-calorie diet and regular physical activity.

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Mechanism Of Action Of Naltrexone/Bupropion

• Naltrexone is an opioid antagonist that modulates the central reward system.
• Bupropion is a norepinephrine and dopamine reuptake inhibitor that affects appetite regulatory pathways in the brain.
• The combination helps to reduce food intake and control cravings, supporting weight loss.

Therapeutic Indications Of Contrave

• Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of:
  • ≥30 kg/m² (obese), or
  • ≥27 kg/m² (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes, or dyslipidemia).

Method Of Administration Of Contrave

• Take orally with food, preferably in the morning and evening.
• Swallow the tablet whole without crushing, chewing, or dividing.
• Follow the dose escalation schedule provided by your doctor to minimize side effects.

Undesirable Side Effects Of Contrave

May cause:

1. Nausea
2. Constipation
3. Headache
4. Dizziness
5. Dry mouth
6. Insomnia
7. Anxiety

Pregnancy & Breastfeeding Precaution While Taking Contrave

• Contraindicated during pregnancy.
• Not recommended during breastfeeding due to potential risks to the infant.

Warnings & Special Precautions While Taking Contrave

• Contraindicated in patients with uncontrolled hypertension, seizure disorders, bulimia, or anorexia nervosa.
• Risk of suicidal thoughts and behaviors, especially at the beginning of treatment or during dose adjustments.
• Monitor blood pressure and mental status regularly.
• Discontinue immediately if serious allergic reactions or seizures occur.

Storage Conditions Of Contrave

• Store below 25°C.
• Keep in the original package, protected from moisture and light.
• Keep out of reach of children.